JWH-073

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JWH-073
Systematic (IUPAC) name
naphthalen-1-yl-(1-butylindol-3-yl)methanone
Identifiers
CAS number	?
ATC code	?
PubChem	10471670
Chemical data
Formula	C23H21NO
Mol. mass	327.42 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Legal
Routes	?

JWH-073 is an analgesic drug from the aminoalkylindole family, which acts as a cannabinoid agonist at both the CB₁ and CB₂ receptors. It is somewhat selective for the CB₁ subtype, with affinity at this subtype approximately 5x the affinity at CB₂.^[1] The abbreviation JWH stands for John W. Huffman, one of the inventors of the compound.

[edit] References

1. ^ Aung MM, Griffin G, Huffman JW, et al (August 2000). "Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding". Drug Alcohol Depend 60 (2): 133–40. doi:10.1016/S0376-8716(99)00152-0. PMID 10940540. 

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