Isavuconazole


Isavuconazole
Systematic (IUPAC) name
4-[2-[(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
Identifiers
CAS number	?
ATC code	?
PubChem	6918485
Chemical data
Formula	C₂₂H₁₇F₂N₅O S
Mol. mass	437.47 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Isavuconazole is a triazole antifungal currently in Phase III clinical trials.

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v • d • e Antifungals (D01 and J02)

Antibiotics	Griseofulvin • polyene antimycotics (Natamycin, Nystatin)

Topical azoles	imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Neticonazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole)

Other topicals	Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine)

For systemic use	Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin)

Other	Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle