Histamine N-methyltransferase

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histamine N-methyltransferase
Identifiers
Symbol	HNMT
Entrez	3176
HUGO	5028
OMIM	605238
RefSeq	NM_006895
UniProt	P50135
Other data
EC number	2.1.1.8
Locus	Chr. 2 q22.1

Histamine N-methyltransferase is an enzyme involved in the metabolism of histamine.

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• MeSH Histamine+N-Methyltransferase

v • d • e Transferase: one carbon transferases (EC 2.1) 2.1.1 - Methyltransferases N-methyltransferase: Histamine N-methyltransferase - Phenylethanolamine N-methyltransferase - Tryptamine N-methyltransferase - Phosphatidylethanolamine N-methyltransferase O-methyltransferase: 5-hydroxyindole-O-methyltransferase/Acetylserotonin O-methyltransferase - Catechol-O-methyl transferase homocysteine methyltransferase: Betaine-homocysteine methyltransferase - Homocysteine methyltransferase - 5-Methyltetrahydrofolate-homocysteine methyltransferase Other: Phosphatidyl ethanolamine methyltransferase - DNMT3B - Histone methyltransferase - Thymidylate synthase - DNA methyltransferase 2.1.2 - Hydroxy methyl-, Formyl- and Related Transferases Serine hydroxymethyltransferase - Phosphoribosylglycinamide formyltransferase - Inosine monophosphate synthase - Glutamate formimidoyltransferase - Aminomethyltransferase 2.1.3 - Carboxy- and Carbamoyl transferases Ornithine transcarbamylase 2.1.4 - Amidino transferases Arginine:glycine amidinotransferase

v • d • e Metabolism: amino acid metabolism - neurotransmitter enzymes histidine→histamine anabolism: Histidine decarboxylase catabolism: Histamine N-methyltransferase - Amine oxidase tyrosine→dopamine→epinephrine anabolism: Tyrosine hydroxylase - Aromatic L-amino acid decarboxylase - Dopamine beta hydroxylase - Phenylethanolamine N-methyltransferase catabolism: Catechol-O-methyl transferase - Monoamine oxidase glutamate→GABA anabolism: Glutamate decarboxylase catabolism: 4-aminobutyrate aminotransferase tryptophan→serotonin→melatonin Tryptophan hydroxylase - Aromatic L-amino acid decarboxylase - Acetylserotonin O-methyltransferase arginine→NO Nitric oxide synthase (NOS1, NOS2A, NOS3) see also intermediates