Hexetidine
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Hexetidine
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| Systematic (IUPAC) name | |
| 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine | |
| Identifiers | |
| CAS number | |
| ATC code | A01 |
| PubChem | |
| Chemical data | |
| Formula | C21H45N3 |
| Mol. mass | 339.602 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Topical (mouthwash) |
Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.[1][2]
Hexetidine is the medicinal ingredient in Sterisol, which is labelled for "the symptomatic treatment of 'strep' throat, tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery."
In the UK, Hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. This is produced by Pfizer. Oraldene mouthwash contains 0.1g/100ml of Hexetidine. In some European countries, the gargle solution and mouth spray in bottles of 40ml named "Hexoral" (by Pfizer) also contains 0.2% Hexetidine as its active compound. Hexetidine can also be found in the mouthwash "Bactidol" (by Pfizer) which is sold in many Asian countries.
[edit] External links
- European Agency for the Evaluation of Medicinal Products overview of the medicinal properties
- netDoctor
[edit] References
- ^ Kapić E, Becić F, Becić E (2002). "Hexetidine--an oral antiseptic". Med Arh 56 (1): 43–8. PMID 11917691.
- ^ Oraldene. NetDoctor.co.uk (July 8, 2004). Retrieved on 2007-04-03.
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