Guanosine diphosphate

Guanosine diphosphate

Identifiers
CAS number	[146-91-8]
PubChem	730
SMILES	C1=NC2=C(N1C3C(C(C(O3)COP (=O)(O)OP(=O)(O)O)O)O)NC(=NC2=O)N
Properties
Molecular formula	C₁₀H₁₅N₅O₁₁P₂
Molar mass	443.200522
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Guanosine diphosphate, abbreviated GDP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase guanine.

GDP is the product of GTP dephosphorylation by GTPases, e.g. the G-proteins that are involved in signal transduction.

Biologically GDP is converted into GTP with the help of pyruvate kinase and phosphoenolpyruvate

[edit] See also

v • d • e Nucleobases, nucleosides, and nucleotides

Nucleobases	Purine (Adenine, Guanine) \| Pyrimidine (Uracil, Thymine, Cytosine)

Nucleosides	Adenosine/Deoxyadenosine \| Guanosine/Deoxyguanosine \| Uridine \| Thymidine \| Cytidine/Deoxycytidine

Nucleotides	monophosphates (AMP, GMP, UMP, CMP) \| diphosphates (ADP, GDP, UDP, CDP) \| triphosphates (ATP, GTP, UTP, CTP) \| cyclic (cAMP, cGMP, cADPR)

Deoxynucleotides	monophosphates (dAMP, dGMP, dUMP, TMP, dCMP) \| diphosphates (dADP, dGDP, TDP, dCDP) \| triphosphates (dATP, dGTP, TTP, dCTP)