Follicular dendritic cells

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Follicular dendritic cells (FDC) are cells of the immune system found in lymph follicles.^[1] They are probably not of hematopoietic origin, but simply look similar to true dendritic cells.^[2] They share their appearance and some aspects of their function with the other types of dendritic cells. They are, however, classified differently in MeSH. ^[3]

They assist in B cell maturation by the presentation of intact antigen to the B cells. This occurs in the germinal centers of peripheral lymphoid organs and induces class switching and proliferation.

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v • d • e Blood General Plasma - Hematopoietic stem cells Lymphoid - WBC T cells: Cytotoxic CD8+, Helper CD4+/Regulatory, γδ, Natural Killer T cell B cells: Plasma, Memory Natural killer cells (Lymphokine-activated killer cell) Null cell Myeloid - WBC Monocytes/Macrophages (Histiocytes, Kupffer cells, Langhans giant cells, Microglia, Osteoclasts) Granulocytes (Neutrophil, Eosinophil, Basophil) - Mast cell precursors Dendritic cells (Langerhans cells, Follicular dendritic cells Megakaryoblast - Megakaryocyte - Platelets Myeloid - RBC Reticulocyte - Normoblast