Megakaryoblast

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A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte during haematopoiesis. It is the beginning of the thrombocytic series.

It derives from a CFU-Me colony unit of pluripotential hemopoietic stem cells.

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• Life cycle

v • d • e Blood General Plasma - Hematopoietic stem cells Lymphoid - WBC T cells: Cytotoxic CD8+, Helper CD4+/Regulatory, γδ, Natural Killer T cell B cells: Plasma, Memory Natural killer cells (Lymphokine-activated killer cell) Null cell Myeloid - WBC Monocytes/Macrophages (Histiocytes, Kupffer cells, Langhans giant cells, Microglia, Osteoclasts) Granulocytes (Neutrophil, Eosinophil, Basophil) - Mast cell precursors Dendritic cells (Langerhans cells, Follicular dendritic cells Megakaryoblast - Megakaryocyte - Platelets Myeloid - RBC Reticulocyte - Normoblast