Flupirtine
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Flupirtine
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| Systematic (IUPAC) name | |
| ethyl {2-amino-6-[(4-fluorobenzyl)amino]pyridin-3-yl}carbamate | |
| Identifiers | |
| CAS number | |
| ATC code | N02 |
| PubChem | |
| Chemical data | |
| Formula | C15H17FN4O2 |
| Mol. mass | 304.32 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Flupirtine is an aminopyridine.
It has been used as an analgesic.[1]
It has been proposed as a possible treatment for Batten disease.[2]
[edit] References
- ^ Swedberg MD, Shannon HE, Nickel B, Goldberg SR (September 1988). "Pharmacological mechanisms of action of flupirtine: a novel, centrally acting, nonopioid analgesic evaluated by its discriminative effects in the rat". J. Pharmacol. Exp. Ther. 246 (3): 1067–74. PMID 2901483.
- ^ Dhar S, Bitting RL, Rylova SN, et al (April 2002). "Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons". Ann. Neurol. 51 (4): 448–66. PMID 11921051.
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