Clofibride


Clofibride
Systematic (IUPAC) name
4-(dimethylamino)-4-oxobutyl 2-(4-chlorophenoxy)-2-methylpropanoate
Identifiers
CAS number	26717-47-5
ATC code	C10AB10
PubChem	160134
Chemical data
Formula	C₁₆H₂₂Cl N O₄
Mol. mass	327.803 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	Hydrolyzed to clofibric acid; hepatic glucuronidation
Half life	12 hours (clofibric acid)
Excretion	Renal (mostly) and fecal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Clofibride is a fibrate.

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v • d • e Lipid modifying agents (C10)

Statins	Atorvastatin • Cerivastatin^‡ • Fluvastatin • Lovastatin • Mevastatin • Pitavastatin • Pravastatin • Rosuvastatin • Simvastatin

Fibrates	Clofibrate^‡ • Bezafibrate • Aluminium clofibrate • Gemfibrozil • Fenofibrate • Simfibrate • Ronifibrate • Ciprofibrate • Etofibrate • Clofibride

Bile acid sequestrants	Colestyramine • Colestipol • Colextran • Colesevelam

Niacin and derivatives	Niceritrol • Niacin • Nicofuranose• Aluminium nicotinate• Nicotinyl alcohol • Acipimox

CETP inhibitors	Anacetrapib^† • Torcetrapib^§

Combinations	Niacin/lovastatin • Niacin/simvastatin • Ezetimibe/simvastatin

Other	Dextrothyroxine • Probucol • Tiadenol • Benfluorex • Meglutol • Omega-3-triglycerides • Magnesium pyridoxal 5-phosphate glutamate • Policosanol • Ezetimibe • Laropiprant^†, Lapaquistat^§

^†Undergoing clinical trials. ^‡Withdrawn from market. ^§Development terminated.