Ceramidase

From Wikipedia, the free encyclopedia

Ceramidase is an enzyme which cleaves fatty acids from ceramide, producing sphingosine.

A deficiency is associated with Farber disease.

[edit] Genes

• ASAH1, ASAH2, ASAH2B, ASAH2C, ASAH3

[edit] External links

• MeSH Ceramidase
• EC 3.5.1.23

v • d • e Carbon-nitrogen non-peptide hydrolases (EC 3.5) 3.5.1 - Amidohydrolases Asparaginase - Glutaminase - Urease - Biotinidase - Aspartoacylase - Ceramidase -Aspartylglucosaminidase - Fatty acid amide hydrolase - Histone deacetylase (Sirtuin) 3.5.2 Barbiturase - Beta-lactamase 3.5.3 Arginase - Agmatinase 3.5.4 - Aminohydrolases Guanine deaminase - Adenosine deaminase - AMP deaminase - Inosine monophosphate synthase - DCMP deaminase - GTP cyclohydrolase I Other Nitrilase - Thiaminase II

v • d • e Metabolism: lipid metabolism - glycolipid/sphingolipid enzymes To glycosphingolipid Glycosyltransferase - Sulfotransferase To ceramide From ganglioside: Beta-galactosidase - Hexosaminidase A - Neuraminidase - Beta-galactosidase - Glucocerebrosidase From globoside: Hexosaminidase B - Alpha-galactosidase - Beta-galactosidase - Glucocerebrosidase From sphingomyelin: Sphingomyelin phosphodiesterase 1 From sulfatide: Arylsulfatase A - Galactosylceramidase To sphingosine Ceramidase Other Serine C-palmitoyltransferase (SPTLC1) see also lipid storage disorders