Cathine

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Cathine
Systematic (IUPAC) name
2-amino-1-phenyl-propan-1-ol
Identifiers
CAS number 492-39-7
ATC code A08AA07
PubChem 441457
Chemical data
Formula C9H13NO 
Mol. mass 151.206
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status

Schedule IV(US)
Routes Chewing Catha edulis leaves.
For the alkaloid found in plants such as coffee and tea, see Caffeine.

Cathine (D-norpseudoephedrine) is a monoamine alkaloid found in the shrub Catha edulis (khat).

Contents

[edit] Pharmacology

Closely related to ephedrine, cathinone and other amphetamines, it may contribute to the stimulant effect of Catha edulis, although another constituent, cathinone appears to show stronger activity. Cathine is one of the optical isomers of phenylpropanolamine, an appetite suppressant and decongestant which is possibly associated with an increased risk of hemorrhagic stroke.

[edit] Regulation

The World Anti-Doping Agency's list of prohibited substances (used for the Olympic Games among other athletic events) bars cathine in concentrations of over 5 micrograms per milliliter in urine. Cathine is a Schedule III drug under the Convention on Psychotropic Substances.[1] In the United States, it is classified as a Schedule IV controlled substance.

Cathine is found in shrub Catha edulis.
Cathine is found in shrub Catha edulis.

In Hong Kong, cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. It can only be used legally by health professionals and for university research purposes. The substance can be given by pharmacists under a prescription. Anyone who supplies the substance without prescription can be fined $10000 (HKD). The penalty for trafficking or manufacturing the substance is a $5,000,000 (HKD) fine and life imprisonment. Possession of the substance for consumption without license from the Department of Health is illegal with a $1,000,000 (HKD) fine and/or 7 years of jail time.

[edit] References

  1. ^ List of pychotropic substances under international control (pdf)

[edit] See also

v • d • e
Amphetamines (N06BA)
v • d • e
Antiobesity preparations (A08)
Centrally acting
Peripherally acting
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