Talk:Bone marrow

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"The tissue of bone marrow, where pluripotential hematopoietic stem cells produce blood cells, is called "myeloid tissue". Disruption of the normal myeloid tissue by cancer is the cause of two forms of leukemia." Actually, the marrow contains myeloid and lymphoid cells. All forms of leukemia (not just the myeloid forms) originate in the bone marrow. I've revised this sentence - comments? MastCell 04:33, 1 August 2006 (UTC)

Contents 1 how bone marrow works? 2 Difference between red and yellow marrow? 3 Marrow as metaphor 4 Article Bias 5 Poorly written

[edit] how bone marrow works?

Just curious as to how the blood cells made by the marrow get into the blood stream?

As the cells mature, they lose various surface "adhesion" molecules that make them "stick" to the bone marrow, and they float loose into the blood. That's a vague hand-waving explanation that will probably get me laughed at, but that's the general idea. MastCell 15:51, 17 August 2006 (UTC)

Also, the image of the leukemic (blast) cells is not a bone marrow. It is a peripheral blood smear. 167.94.2.9 (talk) 07:44, 1 February 2008 (UTC) EAY, MT (ASCP)

[edit] Difference between red and yellow marrow?

The intro says that bone marrow is the place where blood cells originate, but is that true for yellow marrow? The difference between yellow and red marrow should be explained in the article. AxelBoldt 22:19, 15 October 2006 (UTC)

Yellow marrow is just marrow with fat in it. - Nunh-huh 01:06, 16 October 2006 (UTC)

For what little I've read, there's a definite difference between red and yellow that needs explication. As I understand, we start developmentally with red marrow and, as we age, develop yellow marrow. Yellow marrow also either doesn't produce blood cells at all or produces only a few kinds.Satarnion 03:33, 17 October 2006 (UTC)

Actually we are born with both yellow and red marrow , but it isn't true that the yellow marrow is just all fat becuz white blood cells can actually develop in yellow marrow but not all the time and BOTH yellow and red marrow have fat cells on it.. =] Pretty Ricky aint breakin up yall! yay!! Tam` Tam` =] 04:23, 3 April 2007 (UTC)

Red marrow and yellow marrow are descriptive terms for the appearance of the bone marrow to the naked eye. In humans, the red marrow occupies the central (axial) skeleton (skull, vertebrae, ribs, pelvis) and the most proximal parts of the humerus and femur. The remainder of the skeleton is yellow marrow. At a light microscopic level, red marrow contains both haemopoietic (blood cell precursor) cells and fat cells. Yellow marrow is almost all fat cells. In some disease states (anaemia, leukaemia), marrow sites that were yellow can turn red as haemopoiesis starts taking place there.(Jon salisbury 11:15, 28 June 2007 (UTC))

I can't figure out why someone erased "unknown" a couple edits ago...

[edit] Marrow as metaphor

Bones and skeletons in iconography and world symbolism may be understood as metaphorical of the unseen or myserious structure and design that holds, orders and contains the patterns of being extant and extinct in the Universe. By metaphorical extension, marrow is the quintessential at the core of the hidden structure: Mystery.^{[citation needed]}

[edit] Article Bias

This article is not only poorly written (alas most of Wikipedia is), but is also biased toward humans. Is it not true that most non invertebrate life has this sort of tissue? Perhaps an issue of unbiasing this article could be acomplisherd? Ask D.N.A.- Peter Napkin (talk) 04:40, 16 March 2008 (UTC)

[edit] Poorly written

Under "diseases": "What is it I bet you're asking, well..."

That's unacceptable. 71.11.215.216 (talk) 04:23, 21 May 2008 (UTC)