Basket cell

Basket cell
Transverse section of a cerebellar folium (Basket cell labeled at bottom left)
Location	Cerebellum
Function	Inhibitory interneuron
Morphology	multipolar
Presynaptic connections	Parallel fibers
Postsynaptic connections	Purkinje cells

Basket cells are inhibitory GABAergic interneurons found in several brain regions: the molecular layer of the cerebellum, the hippocampus, and the cortex. In the cerebellum, they synapse on the cell bodies of Purkinje cells, and are multipolar and stellate, with freely branching dendrites, which are dilated and knotty. Hippocampal basket cells target somata and proximal dendrites of pyramidal neurons. Cortical and hippocampal basket cells are parvalbumin-expressing and fast-spiking.

Microcircuitry of the cerebellum. Excitatory synapses are denoted by (+) and inhibitory synapses by (-).
Basket cell labeled BC

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v • d • e Brain: Metencephalon/rhombencephalon - cerebellum (hindbrain)

Regions	Posterior lobe (Horizontal fissure) • Anterior lobe • Flocculonodular lobe (Flocculus, Nodule) Vermis: posterior (Folium, Tuber, Uvula) - anterior (Central lobule, Culmen, Lingula) Hemisphere: posterior (Biventer lobule, Cerebellar tonsil) - anterior (Alar central lobule) white: Arbor vitae Vallecula of cerebellum - Primary fissure

Layers	Molecular layer (Stellate cell, Basket cell) Purkinje cell layer (Purkinje cell) Granule cell layer (Golgi cell, Granule cell) Fibers: Mossy fibers • Climbing fiber • Parallel fiber

Deep cerebellar nuclei	Dentate - interposed (Emboliform, Globose) - Fastigial

Peduncles	Inferior (medulla): Dorsal spinocerebellar tract - Olivocerebellar tract - Cuneocerebellar tract - Juxtarestiform body (Vestibulocerebellar tract) Middle (pons): Pontocerebellar fibers Superior (midbrain): Ventral spinocerebellar tract - Dentatothalamic tract - Trigeminocerebellar fibers