Anistreplase

From Wikipedia, the free encyclopedia

Image:Anistreplase.png
Anistreplase
Systematic (IUPAC) name
?
Identifiers
CAS number	81669-57-0
ATC code	B01AD03
PubChem	?
DrugBank	BTD00102
Chemical data
Formula	C2569H3928N746O781S40
Mol. mass	59042.3 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	90 minutes
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Anistreplase is a thrombolytic drug. It converts plasminogen to plasmin, which in turn degrades fibrin (blood clots) to fibrin split products.

Also known as anisoylated plasminogen streptokinase activator complex (APSAC)

v • d • e Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01) Vitamin K antagonists Acenocoumarol • Clorindione • Coumatetralyl • Dicumarol (Dicoumarol) • Diphenadione • Ethyl biscoumacetate • Phenprocoumon • Phenindione • Tioclomarol • Warfarin Heparin group Antithrombin III • Danaparoid • Heparin • Sulodexide • low molecular weight heparin (Bemiparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) Glycoprotein IIb/IIIa inhibitors Abciximab • Eptifibatide • Tirofiban Other platelet aggregation inhibitors Acetylsalicylic acid/Aspirin • Aloxiprin • Ditazole • Carbasalate calcium • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal • ADP receptor inhibitors (Clopidogrel, Ticlopidine, Prasugrel) • prostaglandin analogue (Beraprost, Prostacyclin, Iloprost, Treprostinil) Enzymes plasminogen activators (Alteplase/Reteplase/Tenecteplase, Streptokinase, Urokinase/Saruplase, Anistreplase) • other serine endopeptidases (Ancrod, Drotrecogin alfa/Protein C, Fibrinolysin) • Brinase Direct thrombin inhibitors Argatroban • Bivalirudin • Dabigatran • Desirudin • Hirudin • Lepirudin • Melagatran • Ximelagatran Other antithrombotics Apixaban • Defibrotide • Dermatan sulfate • Fondaparinux • Idraparinux • Otamixaban • Rivaroxaban Non-medicinal Citrate • EDTA • Oxalate