5-phosphoribosyl-4-carboxy-5-aminoimidazole

From Wikipedia, the free encyclopedia

5-phosphoribosyl-4-carboxy-5-aminoimidazole
IUPAC name	5-amino-1-[3,4-dihydroxy-5-(phosphonooxymethyl)- 2-tetrahydrofuranyl]-4-imidazolecarboxylic acid
Identifiers
CAS number
PubChem	1010
SMILES	C1=NC(=C(N1C2C(C(C(O2)COP(=O)(O)O)O)O)N)C(=O)O
Properties
Molecular formula	C9H14N3O9P
Molar mass	339.195921
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

5-phosphoribosyl-4-carboxy-5-aminoimidazole (or CAIR) is an intermediate in the formation of purines.

It is formed by phosphoribosylaminoimidazole carboxylase.

v • d • e Nucleotide metabolic intermediates Purine metabolism Anabolism R5P->IMP: R5P - PRPP - PRA - GAR - FGAR - FGAM - AIR - CAIR - SAICAR - AICAR - FAICAR IMP->AMP: Adenylosuccinate IMP->GMP: Xanthosine monophosphate Catabolism Hypoxanthine - Xanthine - Uric acid Pyrimidine metabolism Anabolism Carbamoyl phosphate - Carbamoyl aspartic acid - 4,5-Dihydroorotic acid - Orotic acid - Orotidine 5'-monophosphate - Uridine monophosphate Catabolism uracil: Dihydrouracil - 3-Ureidopropionic acid - Beta-alanine thymine: Dihydrothymine - beta-ureidoisobutyric acid - 3-Aminoisobutyric acid see also enzymes, disorders