Xanthoxin dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a xanthoxin dehydrogenase (EC 1.1.1.288) is an enzyme that catalyzes the chemical reaction

xanthoxin + NAD⁺ abscisic aldehyde + NADH + H⁺

Thus, the two substrates of this enzyme are xanthoxin and NAD⁺, whereas its 3 products are abscisic aldehyde, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is xanthoxin:NAD+ oxidoreductase. Other names in common use include xanthoxin oxidase, and ABA2. This enzyme participates in carotenoid biosynthesis.

[edit] References

• IUBMB entry for 1.1.1.288
• BRENDA references for 1.1.1.288 (Recommended.)
• PubMed references for 1.1.1.288
• PubMed Central references for 1.1.1.288
• Google Scholar references for 1.1.1.288
• Sindhu RK and Walton DC (1988). "Xanthoxin metabolism in cell-free preparations from wild type and wilty mutants of tomato". Plant Physiol. 88: 178–182. 
• Schwartz SH, Leon-Kloosterziel KM, Koornneef M, Zeevaart JA (1997). "Biochemical characterization of the aba2 and aba3 mutants in Arabidopsis thaliana". Plant. Physiol. 114: 161–6. doi:10.1104/pp.114.1.161. PMID 9159947. 
• Ponce MR, Micol JL, Serrano R, Rodriguez PL (2002). "The short-chain alcohol dehydrogenase ABA2 catalyzes the conversion of xanthoxin to abscisic aldehyde". Plant. Cell. 14: 1833–46. doi:10.1105/tpc.002477. PMID 12172025. 

[edit] External links

• IUBMB entry for 1.1.1.288

• KEGG entry for 1.1.1.288

• BRENDA entry for 1.1.1.288

• NiceZyme view of 1.1.1.288

• EC2PDB: PDB structures for 1.1.1.288

• PRIAM entry for 1.1.1.288

• PUMA2 entry for 1.1.1.288

• IntEnz: Integrated Enzyme entry for 1.1.1.288

• MetaCyc entry for 1.1.1.288

• Atomic-resolution structures of enzymes belonging to this class