Uronate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, an uronate dehydrogenase (EC 1.1.1.203) is an enzyme that catalyzes the chemical reaction

D-galacturonate + NAD⁺ + H₂O D-galactarate + NADH + H⁺

The 3 substrates of this enzyme are D-galacturonate, NAD⁺, and H₂O, whereas its 3 products are D-galactarate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is uronate:NAD+ 1-oxidoreductase. Other names in common use include uronate: NAD-oxidoreductase, and uronic acid dehydrogenase.

[edit] References

• IUBMB entry for 1.1.1.203
• BRENDA references for 1.1.1.203 (Recommended.)
• PubMed references for 1.1.1.203
• PubMed Central references for 1.1.1.203
• Google Scholar references for 1.1.1.203
• KILGORE WW, STARR MP (1959). "Uronate oxidation by phytopathogenic pseudomonads". Nature. 183: 1412–3. doi:10.1038/1831412a0. PMID 13657147. 

[edit] External links

The CAS registry number for this enzyme class is 37250-98-9.

• IUBMB entry for 1.1.1.203

• KEGG entry for 1.1.1.203

• BRENDA entry for 1.1.1.203

• NiceZyme view of 1.1.1.203

• EC2PDB: PDB structures for 1.1.1.203

• PRIAM entry for 1.1.1.203

• PUMA2 entry for 1.1.1.203

• IntEnz: Integrated Enzyme entry for 1.1.1.203

• MetaCyc entry for 1.1.1.203

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050388: uronate dehydrogenase

• AMIGO entry for GO code 0050388: uronate dehydrogenase