Talk:Uric acid

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Contents

[edit] I

I thought 3 to 7ml was the normal range. I had a test recently, and that's what the doctor said about the range. Mine was up about 8.
JesseG 22:19, July 27, 2005 (UTC)


did some page formating only. I'll grab the providers MSDS form the lab when i get the chance and fill in the blanks --Ajusted dog 02:16, 6 August 2005 (UTC)

[edit] Cleanup

1. "Uric acid is a minor end-product of nitrogen metabolism in the human body (the main product being urea), and is found in small amounts in urine.".......... actually the article should be more specific and say that uric acid is the product of PURINE CATABOLISM.


2. "A percentage of gout patients eventually get uric kidney stones" ..........What percentage would that be??? If it is significant the actual percentage should be mentioned and cited, if it is not significant than don't mention it at all.


3. "In human blood, uric acid concentrations between 3.6 and 8.3 mg/dL are considered normal by the American Medical Association, although significantly lower levels are common in vegetarians."...........First, these values are incorrect and there is a different normal range for males than for females. Also, a source needs to be cited more specific than just AMA. In addition, we must specify that it is SERUM Uric Acid as there is also a test for urinary uric acid.

(comment on item 3... when something says "in human blood", i'm not likely to interpret that as urinary uric acid level)

According to Stedman's Medical Dictionary and confirmed in the Merck, Normal Uric Acid Values are as follows: Male: 4.5-8.0 mg/dl Female: 2.5-6.2 mg/dl Child: 2.0-5.5mg/dl

Concentration in urine normal range: 250-750 mg over 24 hours for a normal diet.


4. "The disease gout in humans is associated with abnormal levels of uric acid in the system.".......This is far to vague and ambiguous. Abnormal could mean low, which is not associated with gout. What exactly is "The System"? The artice should be more specific istead of using terms like "the system", and it should indicate that gout is assiciated specifically with HYPERURICEMIA, not just "abnormal levels".


5. "While this compound is more energetic than those other wastes, it means that water loss due to elimination can be reduced to a minimum. ."......... I don't understand what this sentence is saying. It does not make sense. Please rewrite it more clearly or explain it some more.

If you all agree, please update this artice. Thank You!


Please suggest what does abnormal level means? and prevention mechanism for controlling uric acid within normal range.

[edit] addenda to "cleanup"

The number of gout sufferers who eventually get UA stones is significant, on the order of 50%, though I don't remember where that number came from (I'm sure it was some pamphlet from my urologist's office, sponsored by the association of healthy urinary somethingorothers).

Abnormal means high; prevention mechanisms range from dietary (avoiding purines, eating cherries and dark berries) to medicinal (allopurinol, see gout page)


[edit] silly question

this might be silly, but is uric acid ever an ingredient in toothpaste? or anything else that humans might consume?? Rachel Ayres 02:56, 16 December 2006 (UTC)

hi rachel i recently added a little section on foods that can elevate uric acid because they contain high purine levels, not sure which foods or items such as toothpaste might contain actual uric acid. i did find this though:


U Urea. Carbamide. Excreted from urine and other bodily fluids. In deodorants, ammoniated dentrifices, mouthwashes, hair colorings, hand creams, lotions, shampoos, etc. Used to "brown" baked goods, such as pretzels. Derivatives: Imidazolidinyl Urea, Uric Acid. Alternatives: synthetics.

Uric Acid. (See Urea.)

[1]


thank you very much for the info, I did a bit more research (there is some good info on the urea page) and I am not certain, but believe that it is likely most urea or uric acid used in common products (deoderant, pretzels etc.) is synthetic.

but if anyone has different info please pass it on!!

Rachel Ayres 23:22, 24 December 2006 (UTC)

[edit] question for beetstra

hi there what did you mean about RV to (long number) and referencing popups and removal of data? could you please clarify that comment, i'd like to know exactly what happened there, thanks.—Preceding unsigned comment added by 129.97.39.125 (talkcontribs)

I am sorry, without a link it is very difficult for me to say what you refer to, I probably reverted an edit, but I haven't reverted it on uric-acid. Could you please clarify. By the way, if you want to contact a person, it is easier to ask them on their talk page. --Dirk Beetstra T C 17:38, 12 January 2007 (UTC)

[edit] three year of pain

i want to say that i had suffered a lot because of this dan uric acid technical jargons have no meaning for me what i want is that please someone just let me know what causes this in very layman terms and yes which body part might be getting damaged due to this what kind of food are available to trackle this disease and apart from that purine stuff ok..... mail at [REMOVED] —The preceding unsigned comment was added by 208.49.241.227 (talk) 08:21, 9 April 2007 (UTC).

Try this article for a list of foods that are bad for someone with high uric acid. WhatamIdoing (talk) 07:34, 22 January 2008 (UTC)

[edit] diagram

can someone please add a lewis dot diagram to the top of this article, those coloured spheres are not very useful —Preceding unsigned comment added by 121.79.12.115 (talk) 11:15, 23 October 2007 (UTC)

[edit] Why Acid

Why is it called an acid when there are so many amino components or R-N-R analogues? —Preceding unsigned comment added by Jokem (talkcontribs) 19:04, 13 March 2008 (UTC)

It is a weak organic acid. I.e., it dissociates so that protons (hydrogen atoms) come off in solution.Pproctor (talk) 20:50, 24 March 2008 (UTC)

Thanks, but that does not answer why it does this. Amino groups are normally proton acceptors, not donors. Very strange. Jokem (talk) 15:21, 26 March 2008 (UTC)