tRNA-queuosine beta-mannosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a tRNA-queuosine beta-mannosyltransferase (EC 2.4.1.110) is an enzyme that catalyzes the chemical reaction

GDP-mannose + tRNAAsp-queuosine GDP + tRNAAsp-O-5"-beta-D-mannosylqueuosine

Thus, the two substrates of this enzyme are GDP-mannose and tRNAAsp-queuosine, whereas its two products are GDP and [[tRNAAsp-O-5-beta-D-mannosylqueuosine]].

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:tRNAAsp-queuosine O-5"-beta-D-mannosyltransferase.

[edit] References

• IUBMB entry for 2.4.1.110
• BRENDA references for 2.4.1.110 (Recommended.)
• PubMed references for 2.4.1.110
• PubMed Central references for 2.4.1.110
• Google Scholar references for 2.4.1.110
• Okada N, Nishimura S (1977). "Enzymatic synthesis of Q nucleoside containing mannose in the anticodon of tRNA: isolation of a novel mannosyltransferase from a cell-free extract of rat liver". Nucleic. Acids. Res. 4: 2931–8. PMID 20603. 

[edit] External links

The CAS registry number for this enzyme class is 9055-06-5.

• IUBMB entry for 2.4.1.110

• KEGG entry for 2.4.1.110

• BRENDA entry for 2.4.1.110

• NiceZyme view of 2.4.1.110

• EC2PDB: PDB structures for 2.4.1.110

• PRIAM entry for 2.4.1.110

• PUMA2 entry for 2.4.1.110

• IntEnz: Integrated Enzyme entry for 2.4.1.110

• MetaCyc entry for 2.4.1.110

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0016438: tRNA-queuosine beta-mannosyltransferase

• AMIGO entry for GO code 0016438: tRNA-queuosine beta-mannosyltransferase