Thyronamine
From Wikipedia, the free encyclopedia
| Thyronamine | |
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| Identifiers | |
| CAS number | [500-78-7] |
| PubChem | |
| MeSH | |
| Properties | |
| Molecular formula | C14H15NO2 |
| Molar mass | 229.274 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).
The group includes:
- Thyronamine (T0AM)
- 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), a G protein-coupled receptor located in the cell membrane.
- 3,5-Diiodothyronamine (T2AM)
- 3,5,3'-Triiodothyronamine (T3AM)
