Survival of motor neuron
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| Identifiers | |
| Symbol | SMN1 |
| Alt. Symbols | SMA@, SMA |
| Entrez | 6606 |
| HUGO | 11117 |
| OMIM | 600354 |
| RefSeq | NM_000344 |
| UniProt | Q16637 |
| Other data | |
| Locus | Chr. 5 q13 |
|
survival of motor neuron 2, centromeric
|
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| Identifiers | |
| Symbol | SMN2 |
| Entrez | 6607 |
| HUGO | 11118 |
| OMIM | 601627 |
| RefSeq | NM_017411 |
| UniProt | Q16637 |
| Other data | |
| Locus | Chr. 5 q13 |
Survival of motor neuron is a protein associated with spinal muscular atrophy.
A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1]
[edit] See also
[edit] References
- ^ Lunn MR, Root DE, Martino AM, et al (2004). "Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism". Chem Biol 11 (11): 1489–93. doi:. PMID 15555999.
[edit] External links
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