Sulcatone reductase

From Wikipedia, the free encyclopedia

In enzymology, a sulcatone reductase (EC 1.1.1.260) is an enzyme that catalyzes the chemical reaction

sulcatol + NAD⁺ sulcatone + NADH + H⁺

Thus, the two substrates of this enzyme are sulcatol and NAD⁺, whereas its 3 products are sulcatone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is sulcatol:NAD+ oxidoreductase.

[edit] References

• IUBMB entry for 1.1.1.260
• BRENDA references for 1.1.1.260 (Recommended.)
• PubMed references for 1.1.1.260
• PubMed Central references for 1.1.1.260
• Google Scholar references for 1.1.1.260
• Belan A, Botle J, Fauve A, Gourcy JG and Veschambre H (1987). "Use of biological systems for the preparation of chiral molecules 3. An application in pheromone synthesis: Preparation of sulcatol enantiomers". J. Org. Chem. 52: 256–260. doi:10.1021/jo00378a017. 
• Tidswell EC, Salter GJ, Kell DB and Morris JG (1997). "Enantioselectivity of sulcatone reduction by some anaerobic bacteria". Enzyme Microb. Technol. 21: 143–147. doi:10.1016/S0141-0229(96)00264-5. 
• Tidswell EC, Thompson AN and Morris JG (1991). "Selection in chemostat culture of a mutant strain of Clostridium tryobutyricum improved in its reduction of ketones". J. Appl. Microbiol. Biotechnol. 35: 317–322. 

[edit] External links

The CAS registry number for this enzyme class is 196522-54-0.

• IUBMB entry for 1.1.1.260

• KEGG entry for 1.1.1.260

• BRENDA entry for 1.1.1.260

• NiceZyme view of 1.1.1.260

• EC2PDB: PDB structures for 1.1.1.260

• PRIAM entry for 1.1.1.260

• PUMA2 entry for 1.1.1.260

• IntEnz: Integrated Enzyme entry for 1.1.1.260

• MetaCyc entry for 1.1.1.260

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050491: sulcatone reductase

• AMIGO entry for GO code 0050491: sulcatone reductase