Sorbose 5-dehydrogenase (NADP+)

From Wikipedia, the free encyclopedia

In enzymology, a sorbose 5-dehydrogenase (NADP+) (EC 1.1.1.123) is an enzyme that catalyzes the chemical reaction

L-sorbose + NADP⁺ 5-dehydro-D-fructose + NADPH + H⁺

Thus, the two substrates of this enzyme are L-sorbose and NADP⁺, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-sorbose:NADP+ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase, 5-keto-D-fructose reductase, sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate-linked, reductase, and sorbose 5-dehydrogenase (NADP+).

[edit] References

• IUBMB entry for 1.1.1.123
• BRENDA references for 1.1.1.123 (Recommended.)
• PubMed references for 1.1.1.123
• PubMed Central references for 1.1.1.123
• Google Scholar references for 1.1.1.123
• Englard S, Kaysen G, Avigad G (1970). "5-keto-D-fructose. VI. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from yeast". J. Biol. Chem. 245: 1311–8. PMID 4392628. 

[edit] External links

The CAS registry number for this enzyme class is 37250-52-5.

• IUBMB entry for 1.1.1.123

• KEGG entry for 1.1.1.123

• BRENDA entry for 1.1.1.123

• NiceZyme view of 1.1.1.123

• EC2PDB: PDB structures for 1.1.1.123

• PRIAM entry for 1.1.1.123

• PUMA2 entry for 1.1.1.123

• IntEnz: Integrated Enzyme entry for 1.1.1.123

• MetaCyc entry for 1.1.1.123

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050287: sorbose 5-dehydrogenase (NADP+)

• AMIGO entry for GO code 0050287: sorbose 5-dehydrogenase (NADP+)