Serine 3-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a serine 3-dehydrogenase (EC 1.1.1.276) is an enzyme that catalyzes the chemical reaction

L-serine + NADP⁺ 2-ammoniomalonate semialdehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are L-serine and NADP⁺, whereas its 3 products are 2-ammoniomalonate semialdehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-serine:NADP+ 3-oxidoreductase.

[edit] References

• IUBMB entry for 1.1.1.276
• BRENDA references for 1.1.1.276 (Recommended.)
• PubMed references for 1.1.1.276
• PubMed Central references for 1.1.1.276
• Google Scholar references for 1.1.1.276
• Fujisawa H, Nagata S, Chowdhury EK, Matsumoto M, Misono H (2002). "Cloning and sequencing of the serine dehydrogenase gene from Agrobacterium tumefaciens". Biosci. Biotechnol. Biochem. 66: 1137–9. doi:10.1271/bbb.66.1137. PMID 12092831. 
• Chowdhury EK, Higuchi K, Nagata S, Misono H (1997). "A novel NADP(+)-dependent serine dehydrogenase from Agrobacterium tumefaciens". Biosci. Biotechnol. Biochem. 61: 152–7. PMID 9028042. 

[edit] External links

The CAS registry number for this enzyme class is 9038-55-5.

• IUBMB entry for 1.1.1.276

• KEGG entry for 1.1.1.276

• BRENDA entry for 1.1.1.276

• NiceZyme view of 1.1.1.276

• EC2PDB: PDB structures for 1.1.1.276

• PRIAM entry for 1.1.1.276

• PUMA2 entry for 1.1.1.276

• IntEnz: Integrated Enzyme entry for 1.1.1.276

• MetaCyc entry for 1.1.1.276

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0031132: serine 3-dehydrogenase

• AMIGO entry for GO code 0031132: serine 3-dehydrogenase