Talk:Saxitoxin
From Wikipedia, the free encyclopedia
 |
This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme. |
||
| Stub | This article has been rated as stub-Class on the assessment scale. |
||
| Low | This article is on a subject of low-importance within molecular and cellular biology. | ||
|
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need. |
|||
How can you know Saxitoxin is a cause of MS and MSA?
Because it is well known among the best saxitoxin-researchers in my country (Sweden) since a few years back. And I was told I was going to get MS (Multiple Sclerosis) or MSA (Multiple System Athrophy) when I was saxitoxin-poisoned. I did not believe this but 1,5 years later I was severely sick in MSA.
And it is well known there was an outbreak of MS on the Orkney-islands when a group of British soldiers were stationed there. And what do they have there? Yes, Dinoflagelates in the sea who makes Saxitoxin which in turn poisons mussels. Then must the soldiers have taught the islanders how to cook and eat sea-mussels, and then followed the MS-outbreak of course.
And because it is well known that the orthodox Jews don’t get MS. One of the forbidden foodstuff for the orthodox Jews is shellfish that includes sea-mussels which can survive very high concentrations of Saxitoxin because they have ten times thicker neural-threads than other animals and therefor can get very poisonous to humans.
Also MS is an autoimmune disease that attacks the myelin and MSA is an autoimmune disease that attacks the oligodendrocyte-cells, which makes the myelin. It is known that autoimmune diseases can be started by toxins and since these two diseases are so closely related it is also logical they can have the same cause.
Saxitoxin has been starting MS and MSA for billions of years and will continue to do so for billions of years in the future and this has been and will be a fact for the same time-span, and I have learnt this the hard way. It was proven to me by the reality.
- I have to say that I'm a little skeptical that saxiton can cause MS. Saxiton binds binds reversibly to the voltage gated sodium channel of nerve cells, preventing them from opening in the response to an impulse, having the effect of keeping nerves from activating. Multiple sclerosis, however, is an autoimmune disorder that affects the nervous system's myelin. A quick literature search find some reviews that cautiously suggest that saxitoxin may be used to treat MS, but there is nothing that suggests that it is the cause of MS. I'm very sorry to say, but in the absence of hard evidence, your conculsions fall under the heading of "original research". – ClockworkSoul 01:57, 9 May 2005 (UTC)
[edit] FUGU is caused by tetrodotoxin and not saxitoxin
the fugu disease is caused by tetrodotoxin and not saxitoxin ! it can be checked in tetrodotoxin. Redecke 22:51, 8 April 2006 (UTC)
ː Since Saxitoxin binds reversibly to the voltage gated sodium channel of nerve cells, preventing them from opening in the response to an impulse, having the effect of keeping nerves from activating and this condition lasts for about 5 days before the poison is gone. Then there is plenty of time for the immune system to start fighting back against it and when it does this it unfortunately also simultaneously fights the body’s own myelin or oligodendrocyte-cells. When there is no more saxitoxin left in the body the immune system just continues to fight myelin or oligodendrocyte-cells only instead. June 2007
[edit] LCt50
LCt50, given in mg/m³.min is not median lethal dose, but median lethal concentration. It is a difference, so I'll change it.--84.163.126.221 (talk) 23:26, 11 February 2008 (UTC)
