Salicylaldehyde dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a salicylaldehyde dehydrogenase (EC 1.2.1.65) is an enzyme that catalyzes the chemical reaction

salicylaldehyde + NAD⁺ + H₂O salicylate + NADH + 2 H⁺

The 3 substrates of this enzyme are salicylaldehyde, NAD⁺, and H₂O, whereas its 3 products are salicylate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is salicylaldehyde:NAD+ oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.

[edit] References

• IUBMB entry for 1.2.1.65
• BRENDA references for 1.2.1.65 (Recommended.)
• PubMed references for 1.2.1.65
• PubMed Central references for 1.2.1.65
• Google Scholar references for 1.2.1.65
• Eaton RW, Chapman PJ (1992). "Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions". J. Bacteriol. 174: 7542–54. PMID 1447127. 

[edit] External links

• IUBMB entry for 1.2.1.65

• KEGG entry for 1.2.1.65

• BRENDA entry for 1.2.1.65

• NiceZyme view of 1.2.1.65

• EC2PDB: PDB structures for 1.2.1.65

• PRIAM entry for 1.2.1.65

• PUMA2 entry for 1.2.1.65

• IntEnz: Integrated Enzyme entry for 1.2.1.65

• MetaCyc entry for 1.2.1.65

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018485: salicylaldehyde dehydrogenase

• AMIGO entry for GO code 0018485: salicylaldehyde dehydrogenase