Ribitol-5-phosphate 2-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a ribitol-5-phosphate 2-dehydrogenase (EC 1.1.1.137) is an enzyme that catalyzes the chemical reaction

D-ribitol 5-phosphate + NAD(P)+ D-ribulose 5-phosphate + NAD(P)H + H⁺

The 3 substrates of this enzyme are D-ribitol 5-phosphate, NAD⁺, and NADP⁺, whereas its 4 products are D-ribulose 5-phosphate, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase. This enzyme is also called dehydrogenase, ribitol 5-phosphate. This enzyme participates in pentose and glucuronate interconversions.

[edit] References

• IUBMB entry for 1.1.1.137
• BRENDA references for 1.1.1.137 (Recommended.)
• PubMed references for 1.1.1.137
• PubMed Central references for 1.1.1.137
• Google Scholar references for 1.1.1.137
• GLASER L (1963). "Ribitol-5-phosphate dehydrogenase from Lactobacillus plantarum". Biochim. Biophys. Acta. 67: 525–30. doi:10.1016/0006-3002(63)91863-8. PMID 13948358. 

[edit] External links

The CAS registry number for this enzyme class is 37250-67-2.

• IUBMB entry for 1.1.1.137

• KEGG entry for 1.1.1.137

• BRENDA entry for 1.1.1.137

• NiceZyme view of 1.1.1.137

• EC2PDB: PDB structures for 1.1.1.137

• PRIAM entry for 1.1.1.137

• PUMA2 entry for 1.1.1.137

• IntEnz: Integrated Enzyme entry for 1.1.1.137

• MetaCyc entry for 1.1.1.137

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050256: ribitol-5-phosphate 2-dehydrogenase

• AMIGO entry for GO code 0050256: ribitol-5-phosphate 2-dehydrogenase