Talk:Reye's syndrome
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Information from Reye's syndrome appeared on Portal:Medicine in the Did you know section on June 6, 2006. |
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[edit] Cleanup Required
First of all, there are five stages, not two. Also, the symptoms are vague and nonspecific. I'll get this section cleaned up in a jiffity when I have time. Right now is not a good time, at least not for me. Freddie 00:00, 17 March 2006 (UTC)
[edit] Mitochondropathy?
When I was a student at a tertiary neuroological centre, I was taught that Reye's syndrome is one of a family of mitochondrial diseases (mitochondropathies), which explains its multi-system nature and its predominant effects on liver and brain. Unfortunately this now lies well outside my field of expertise. Anyone elucidate? Thanks. Preacherdoc 13:57, 26 July 2006 (UTC)
- MeSH Reye+Syndrome seems to agree with you ("It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and carnitine metabolism") though it doesn't categorize Reye's under MeSH Mitochondrial+Diseases. On the other hand, emerg/399 at eMedicine hedges a bit ("The pathogenesis is unclear, but it appears to involve mitochondrial dysfunction that inhibits oxidative phosphorylation and fatty-acid beta-oxidation in a virus-infected, sensitized host.") At Online 'Mendelian Inheritance in Man' (OMIM) 212140 (primary carnitine deficiency), they use the phrase "Reye-like syndrome". And recent research (PMID 16725361) also seems to point in that direction. Probably worth a mention, both at this article and at mitochondrial disease. --Arcadian 17:33, 26 July 2006 (UTC)
[edit] Pepto-Bismal Connection
I've noticed that bottles of Pepto and its generic versions contain a warning about possibly causing Reye's Syndrome. Shouldn't this get a mention as well? BioTube 18:27, 9 September 2006 (UTC)
- Pepto Bismol (bismuth subsalicylate) contains a salicylate compound in it. Since this article already says that salicylates precipitate the syndrome, there's no need to mention Pepto here. --David Iberri (talk) 14:46, 15 February 2007 (UTC)
[edit] Fat in Liver
Currently, this symptom has links to fat and liver. Would it not be more logical for it to have a link to fatty liver, or is the fat in the liver caused by Reye's Syndrome not the same as fatty liver? --PBurns 22:17, 9 October 2006 (UTC)
[edit] aspirin bias?
The current wikipedia entry for Reye syndrome is biased against aspirin as a potential risk factor, and this view seems to contradict the prevailing consensus of the scientific community on the subject. As a result, the entry has poor credibility, and should be edited.
[edit] Treatment
How is the disease treated? Is the coma reversible? Jack Daw 18:45, 3 December 2006 (UTC)
I'm also curious as to how this is treated. This article doesn't even address it. Can this disease be treated? If so, what is most effective in treating it? -- THL 07:56, 21 December 2006 (UTC)
[edit] Not entirely copyvio
This page is partially a copyvio, but much content is original (e.g. by myself). Would not support deletion. JFW | T@lk 14:48, 20 February 2007 (UTC)
