Relapsing polychondritis

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Relapsing polychondritis Classification and external resources
ICD-10	M94.1
ICD-9	733.99
DiseasesDB	10248
eMedicine	med/2000  derm/375
MeSH	D011081

Relapsing polychondritis is a condition where cartilage deteriorates.

It is also known as Chronic atrophic polychondritis, Meyenburg-Altherr-Uehlinger syndrome, von Meyenburg's disease, Generalized chondromalacia, or Systemic chondromalacia.

Contents 1 Presentation 2 Causes 3 Treatment 4 Onset 5 References 6 External links

[edit] Presentation

All cartilage areas can be affected, though in many cases the disease will affect several areas where cartilage is found in the body, and leave others entirely alone. Parts of the body with cartilage, and therefore potentially affected by polychondritis, include the ears, nose, throat, heart valves and of course all areas where musculo-skeletal tissues are connected by cartilage. Specific resultant conditions may include Type 3 Tracheomalacia and Vasculitis.

[edit] Causes

Reasons for disease onset are not known.

It is considered to possibly be an auto-immune disease^[1] in which the human's body's immune system begins to attack and destroy the cartilage tissues in the body.

[edit] Treatment

Treatment plans typically involve suppression of the immune system with medicines, which often result in a side effect of increasing the risk of other infections.

[edit] Onset

While the disease can come on at various times, most frequent time for onset is in the late 40's to early 50's. Some literature reports a slightly higher occurrence in females than males, while other literature asserts that sex is apparently not a statistically significant factor in the occurrence rate of the disease. Polychondritis is one of many subclasses of disease in the area of Rheumatology.

[edit] References

[edit] External links

• Polychondritis Educational Society, Ltd. (PES)
• Dr. D. E. Trentham research paper
• MedicineNet.com
• The Polychondritis Group - Support Group

v • d • e Diseases of the musculoskeletal system and connective tissue (M, 710-739) Arthropathies Arthritis (Septic arthritis, Reactive arthritis, Rheumatoid arthritis, Psoriatic arthritis, Felty's syndrome, Juvenile idiopathic arthritis, Still's disease) - crystal (Gout, Chondrocalcinosis) - Osteoarthritis (Heberden's node, Bouchard's nodes) acquired deformities of fingers and toes (Boutonniere deformity, Bunion, Hallux rigidus, Hallux varus, Hammer toe, Swan neck deformity) - other acquired deformities of limbs (Valgus deformity, Varus deformity, Wrist drop, Foot drop, Flat feet, Club foot, Unequal leg length, Winged scapula) patella (Luxating patella, Chondromalacia patellae) Protrusio acetabuli - Hemarthrosis - Arthralgia - Osteophyte Systemic CT disorders vasculitis: Churg-Strauss syndrome - Kawasaki disease - Hypersensitivity vasculitis - Wegener's granulomatosis - Arteritis (Polyarteritis nodosa, Takayasu's arteritis, Temporal arteritis) immune/autoimmune: Goodpasture's syndrome - Microscopic polyangiitis - Systemic lupus erythematosus (Drug-induced) - Dermatomyositis (Juvenile dermatomyositis) - Polymyositis - Scleroderma - Sjögren's syndrome - Behçet's disease - Polymyalgia rheumatica - Eosinophilic fasciitis Hypermobility Dorsopathies spinal curvature (Kyphosis, Lordosis, Scoliosis) - Scheuermann's disease - Spondylolysis - Torticollis - Spondylolisthesis Spondylopathies (Ankylosing spondylitis, Spondylosis, Spinal stenosis) - Schmorl's nodes - Degenerative disc disease - Coccydynia - Back pain (Radiculopathy, Neck pain, Sciatica, Low back pain) Soft tissue disorders muscle: Myositis (Pyomyositis) - Myositis ossificans (Fibrodysplasia ossificans progressiva) synovium and tendon: Synovitis/Tenosynovitis (Calcific tendinitis, Stenosing tenosynovitis, Trigger finger, DeQuervain's syndrome) - Irritable hip - Ganglion cyst bursa: bursitis (Olecranon, Prepatellar, Trochanteric) - Baker's cyst fibroblastic disorders: Dupuytren's contracture - Fasciitis (Plantar fasciitis, Nodular fasciitis, Necrotizing fasciitis) - Fibromatosis shoulder lesions: Adhesive capsulitis - Rotator cuff tear - Subacromial bursitis enthesis: enthesopathies (Iliotibial band syndrome, Achilles tendinitis, Patellar tendinitis, Golfer's elbow, Tennis elbow, Metatarsalgia, Bone spur, Tendinitis) other, NEC: Muscle weakness - Rheumatism - Myalgia - Neuralgia - Neuritis - Panniculitis - Fibromyalgia Osteopathies disorders of bone density and structure: Osteoporosis - Osteomalacia - continuity of bone (Pseudarthrosis, Stress fracture) - Monostotic fibrous dysplasia - Skeletal fluorosis - Aneurysmal bone cyst - Hyperostosis - Osteosclerosis Osteomyelitis - Avascular necrosis - Paget's disease of bone - Algoneurodystrophy - Osteolysis - Infantile cortical hyperostosis Chondropathies Juvenile osteochondrosis (Legg-Calvé-Perthes syndrome, Osgood-Schlatter disease, Köhler disease, Sever's disease) - Osteochondritis - Tietze's syndrome - Relapsing polychondritis See also congenital conditions (Q65-Q79, 754-756)