Quinate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a quinate dehydrogenase (EC 1.1.1.24) is an enzyme that catalyzes the chemical reaction

L-quinate + NAD⁺ 3-dehydroquinate + NADH + H⁺

Thus, the two substrates of this enzyme are L-quinate and NAD⁺, whereas its 3 products are 3-dehydroquinate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-quinate:NAD+ 3-oxidoreductase. Other names in common use include quinic dehydrogenase, quinate:NAD oxidoreductase, quinate 5-dehydrogenase, and quinate:NAD+ 5-oxidoreductase. This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis.

[edit] References

• IUBMB entry for 1.1.1.24
• BRENDA references for 1.1.1.24 (Recommended.)
• PubMed references for 1.1.1.24
• PubMed Central references for 1.1.1.24
• Google Scholar references for 1.1.1.24
• Gamborg OL (1966). "Aromatic metabolism in plants. III. Quinate dehydrogenase from mung bean cell suspension cultures". Biochim. Biophys. Acta 128: 483–491. 
• MITSUHASHI S, DAVIS BD (1954). "Aromatic biosynthesis. XIII. Conversion of quinic acid to 5-dehydroquinic acid by quinic dehydrogenase". Biochim. Biophys. Acta. 15: 268–80. doi:10.1016/0006-3002(54)90069-4. PMID 13208693. 

[edit] External links

The CAS registry number for this enzyme class is 9028-28-8.

• IUBMB entry for 1.1.1.24

• KEGG entry for 1.1.1.24

• BRENDA entry for 1.1.1.24

• NiceZyme view of 1.1.1.24

• EC2PDB: PDB structures for 1.1.1.24

• PRIAM entry for 1.1.1.24

• PUMA2 entry for 1.1.1.24

• IntEnz: Integrated Enzyme entry for 1.1.1.24

• MetaCyc entry for 1.1.1.24

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030266: quinate 5-dehydrogenase

• AMIGO entry for GO code 0030266: quinate 5-dehydrogenase