Pyridoxine 4-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a pyridoxine 4-dehydrogenase (EC 1.1.1.65) is an enzyme that catalyzes the chemical reaction

pyridoxine + NADP⁺ pyridoxal + NADPH + H⁺

Thus, the two substrates of this enzyme are pyridoxine and NADP⁺, whereas its 3 products are pyridoxal, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is pyridoxine:NADP+ 4-oxidoreductase. Other names in common use include pyridoxin dehydrogenase, pyridoxol dehydrogenase, and pyridoxine dehydrogenase. This enzyme participates in vitamin b6 metabolism.

[edit] References

• IUBMB entry for 1.1.1.65
• BRENDA references for 1.1.1.65 (Recommended.)
• PubMed references for 1.1.1.65
• PubMed Central references for 1.1.1.65
• Google Scholar references for 1.1.1.65
• HOLZER H, SCHNEIDER S (1961). "[Purification and characterization of a TPN-dependent pyridoxol dehydrogenase from brewers yeast.]". Biochim. Biophys. Acta. 48: 71–6. PMID 13715611. 

[edit] External links

The CAS registry number for this enzyme class is 9028-64-2.

• IUBMB entry for 1.1.1.65

• KEGG entry for 1.1.1.65

• BRENDA entry for 1.1.1.65

• NiceZyme view of 1.1.1.65

• EC2PDB: PDB structures for 1.1.1.65

• PRIAM entry for 1.1.1.65

• PUMA2 entry for 1.1.1.65

• IntEnz: Integrated Enzyme entry for 1.1.1.65

• MetaCyc entry for 1.1.1.65

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050236: pyridoxine 4-dehydrogenase

• AMIGO entry for GO code 0050236: pyridoxine 4-dehydrogenase