Pyridoxal 4-dehydrogenase

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In enzymology, a pyridoxal 4-dehydrogenase (EC 1.1.1.107) is an enzyme that catalyzes the chemical reaction

pyridoxal + NAD⁺ 4-pyridoxolactone + NADH + H⁺

Thus, the two substrates of this enzyme are pyridoxal and NAD⁺, whereas its 3 products are 4-pyridoxolactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is pyridoxal:NAD+ 4-oxidoreductase. This enzyme is also called pyridoxal dehydrogenase. This enzyme participates in vitamin b6 metabolism.

[edit] References

• IUBMB entry for 1.1.1.107
• BRENDA references for 1.1.1.107 (Recommended.)
• PubMed references for 1.1.1.107
• PubMed Central references for 1.1.1.107
• Google Scholar references for 1.1.1.107
• Burg RW, Snell EE (1969). "The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase". J. Biol. Chem. 244: 2585–9. PMID 4306030. 

[edit] External links

The CAS registry number for this enzyme class is 37250-39-8.

• IUBMB entry for 1.1.1.107

• KEGG entry for 1.1.1.107

• BRENDA entry for 1.1.1.107

• NiceZyme view of 1.1.1.107

• EC2PDB: PDB structures for 1.1.1.107

• PRIAM entry for 1.1.1.107

• PUMA2 entry for 1.1.1.107

• IntEnz: Integrated Enzyme entry for 1.1.1.107

• MetaCyc entry for 1.1.1.107

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050235: pyridoxal 4-dehydrogenase

• AMIGO entry for GO code 0050235: pyridoxal 4-dehydrogenase