Pulmonary compliance
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It has been suggested that this article or section be merged into Compliance (physiology). (Discuss) |
Compliance is the ability of the lungs to stretch in a change in volume relative to an applied change in pressure. It is an important measurement in respiratory physiology.[1][2][3]
- fibrosis is associated with a decrease in pulmonary compliance.
- emphysema/COPD are associated with an increase in pulmonary compliance.
Pulmonary surfactant increases compliance.
Compliance is greatest at moderate lung volumes, and much lower at volumes which are very low or very high.
[edit] Calculation
Compliance is calculated using the following equation, where ΔV is the change in volume, and ΔP is the change in pressure:[4]
For example if a patient inhales 500 ml of air from a spirometer and pleural pressure before inspiration is – 5 cm H2O and -10 cm H2O at the end of inspiration. Then: Compliance= DeltaV/DeltaP=.5L/(-5cm H2O- (-10cm H2O))=.5L/5 cm H2O=0.1 L/cm H2O
[edit] References
- ^ Compliance
- ^ Nikischin W, Gerhardt T, Everett R, Bancalari E (1998). "A new method to analyze lung compliance when pressure-volume relationship is nonlinear.". Am J Respir Crit Care Med 158 (4): 1052–60. PMID 9769260. article
- ^ Physiology at MCG 4/4ch2/s4ch2_21
- ^ Vascular compliance
[edit] External links
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