Pterocarpin synthase

From Wikipedia, the free encyclopedia

In enzymology, a pterocarpin synthase (EC 1.1.1.246) is an enzyme that catalyzes the chemical reaction

medicarpin + NADP⁺ + H₂O vestitone + NADPH + H⁺

The 3 substrates of this enzyme are medicarpin, NADP⁺, and H₂O, whereas its 3 products are vestitone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is medicarpin:NADP+ 2'-oxidoreductase. This enzyme is also called pterocarpan synthase. This enzyme participates in isoflavonoid biosynthesis.

[edit] References

• IUBMB entry for 1.1.1.246
• BRENDA references for 1.1.1.246 (Recommended.)
• PubMed references for 1.1.1.246
• PubMed Central references for 1.1.1.246
• Google Scholar references for 1.1.1.246
• Bless W and Barz W (1988). "Isolation of pterocarpan synthase, the terminal enzyme of pterocarpan phytoalexin biosynthesis in cell-suspension cultures of Cicer arietinum". FEBS Lett. 235: 47–50. doi:10.1016/0014-5793(88)81231-6. 

[edit] External links

The CAS registry number for this enzyme class is 118477-70-6.

• IUBMB entry for 1.1.1.246

• KEGG entry for 1.1.1.246

• BRENDA entry for 1.1.1.246

• NiceZyme view of 1.1.1.246

• EC2PDB: PDB structures for 1.1.1.246

• PRIAM entry for 1.1.1.246

• PUMA2 entry for 1.1.1.246

• IntEnz: Integrated Enzyme entry for 1.1.1.246

• MetaCyc entry for 1.1.1.246

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050229: pterocarpin synthase

• AMIGO entry for GO code 0050229: pterocarpin synthase