Propanediol-phosphate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a propanediol-phosphate dehydrogenase (EC 1.1.1.7) is an enzyme that catalyzes the chemical reaction

propane-1,2-diol 1-phosphate + NAD⁺ hydroxyacetone phosphate + NADH + H⁺

Thus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD⁺, whereas its 3 products are hydroxyacetone phosphate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol-1-phosphate:NAD+ oxidoreductase. Other names in common use include PDP dehydrogenase, 1,2-propanediol-1-phosphate:NAD+ oxidoreductase, and propanediol phosphate dehydrogenase.

[edit] References

• IUBMB entry for 1.1.1.7
• BRENDA references for 1.1.1.7 (Recommended.)
• PubMed references for 1.1.1.7
• PubMed Central references for 1.1.1.7
• Google Scholar references for 1.1.1.7
• Sellinger OZ and Miller ON (1959). "The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate dehydrogenase". J. Biol. Chem. 234: 1641–1646. 

[edit] External links

The CAS registry number for this enzyme class is 9028-15-3.

• IUBMB entry for 1.1.1.7

• KEGG entry for 1.1.1.7

• BRENDA entry for 1.1.1.7

• NiceZyme view of 1.1.1.7

• EC2PDB: PDB structures for 1.1.1.7

• PRIAM entry for 1.1.1.7

• PUMA2 entry for 1.1.1.7

• IntEnz: Integrated Enzyme entry for 1.1.1.7

• MetaCyc entry for 1.1.1.7

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050216: propanediol-phosphate dehydrogenase

• AMIGO entry for GO code 0050216: propanediol-phosphate dehydrogenase