Talk:Peripheral neuropathy
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[edit] References
To the author of the article: the links in References do not work any more. Should they be removed?Neven Karlovac 03:06, 8 March 2006 (UTC)
[edit] Q: Gain-of-function vs. loss-of-function symptoms
Could someone go into the difference between gain-of-function and loss-of-function symptoms? I assume that having gain-of-function symptoms is somehow better? Do they indicate that the nerves are healing? If itching is a gain-of-function symptom, does that mean that neuropathic itching is unlikely to be continuing/permanent? Or could someone just have itching for the rest of their lives? -- Creidieki 4 July 2005 18:43 (UTC)
==A?: I had the same Q, and did some extra searching. The PANSS [1] wiki article had the following comment which seems to make sense: "positive symptoms, meaning those symptoms of disease that manifest as the presence of traits, and the syndrome of negative symptoms,meaning those symptoms that manifest as the absence of traits." In this context, the terms "gain of function" and "positve symptom" seem to mean "addition of unexpected or unusual traits or sensations" rather than "restoration of lost functions, or symptoms, of a condition toward normalcy". Would someone with real expertise in this field please confirm this and also update the reference links. Thanks. 208.100.252.61 17:44, 25 February 2007 (UTC)
[edit] Anecdotal Answer
You probably don't want anecdote, but for the sake of satisfying curiousity: I have positive peripheral neuropathy in my feet, resulting from vinblastine therapy for Hodgkin's Lymphoma six years ago. It has become progressively worse over the last few years, to the point where I am only up making this entry (and an edit) because I can't sleep due to it and I'm waiting for some pills to kick in. My symptoms are best described as 24/7 pins-and-needles, ranging from barely noticable or even not noticable, to constant non-ignorable irritation like now, to occasional "stabs" of pain which last a fraction of a second, and which occur on average about once or twice a day. Fortunately for me the times of worse pain come at night, possibly due to being horizontal, so it doesn't prevent me from putting on socks and shoes, walking around, etc. However I cannot have my feet touched -- I startled my poor little niece last year when she innocently tickled my foot and I YELLED in pain: poor thing was startled half to death and it's hard to explain to a two-year-old that everyone else's feet are perfectly good tickling targets while Uncle Chris' aren't :).
I definitely have something to contribute to this topic but I'm certainly not going to throw anecdotes like this in there -- but as I said, for the sake of curiousity fulfillment. -- Tofino 08:46, 6 March 2006 (UTC)
The article states two types of peropheral neuropathy and elaborated on symetrical but there isn't information regarding focal or multifocal perpipheral neuropathy.
[edit] Combine with main neuropathy article!
The article neuropathy states that this term is generally used synonymously with "peripheral neuropathy". I think a redirect is appropriate here, along with combining the two articles into one. Wwallacee 15:48, 27 February 2007 (UTC)
- I disagree. Neuropathy, from what I can gather, refers to ALL types of pathologies of nerves. Peripheral neuropathy is a specific type, not inclusive of a non peripheral neuropathy like radiculopathy. Sure, it generally may be used for peripheral neuropathies, but that's like suggesting we combine the articles bear and brown bear because generally, you are only going to see brown bears. The content may need to be better stratified amongst the two articles (I can't tell I haven't looked them over, and frankly I don't know that I'm qualified), but there ought to be two articles, minimum. Root4(one) 22:57, 6 June 2007 (UTC)
[edit] Is thers some list of or category for peripheral neuropathies?
If such a thing exists, I have a few things to add. carpal tunnel syndrome, ulnar nerve entrapment, etc.Root4(one) 22:59, 6 June 2007 (UTC)
[edit] Hypersensitivity
Is saying that the patients are "prohibited" from having anything touching certain parts of the body accurate? "Prohibited" suggests an authoritative agent, when perhaps the patient finds the experience prohibitive, or possibly the patient prohibitis others from touching certain parts of his body. —Preceding unsigned comment added by Iain marcuson (talk • contribs) 06:25, August 25, 2007 (UTC)
