Omega-hydroxydecanoate dehydrogenase

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In enzymology, an omega-hydroxydecanoate dehydrogenase (EC 1.1.1.66) is an enzyme that catalyzes the chemical reaction

10-hydroxydecanoate + NAD⁺ $\rightleftharpoons$ 10-oxodecanoate + NADH + H⁺

Thus, the two substrates of this enzyme are 10-hydroxydecanoate and NAD⁺, whereas its 3 products are 10-oxodecanoate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-hydroxydecanoate:NAD+ 10-oxidoreductase.

[edit] References

IUBMB entry for 1.1.1.66
BRENDA references for 1.1.1.66 (Recommended.)
PubMed references for 1.1.1.66
PubMed Central references for 1.1.1.66
Google Scholar references for 1.1.1.66
Kamei S, Wakabayashi K and Shimazono M (Tokyo). "omega-Oxidation of fatty acids in vitro. II. omega-Hydroxy fatty acid-NAD oxidoreductase". J. Biochem.: 72–76.
Mitz MA and Henrikson RL (1961). "Omega hydroxy fatty acid dehydrogenase". Biochim. Biophys. Acta 46: 45–50. doi:10.1016/0006-3002(61)90644-8.