Talk:Nociception
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[edit] Lead
Adjust lead to say 'conducts sensation to brain' and remove spinal cord? Spinal cord may be part of the CNS but it doesn't think, so how can it experience pain? It would only conduct. That's my thinking, agree/disagree? WLU (talk) 23:38, 3 April 2008 (UTC)
- Disagree with removal. The word "sensation" here is being used in a technical/jargon way - it refers to non-conscious activity in nerves (that will/may later enter consciousness). (The spinal cord is involved in some processing of the data being carried.)
- "Experience", in the field of pain, is subjective and takes place in consciousness. The brain, while being the physical location, is not refered to as the experiencer of subjective consciousness. "Sentient being" and mind are 2 other places where experience is said to occur.
- A lot of nociception occurs without any conscious experience. As [Nociceptor] says "Nociception can also cause generalized autonomic responses before or without reaching consciousness to cause pallor, diaphoresis, bradycardia, hypotension, lightheadedness, nausea and fainting.
- I would like to find a replacement word for "sensation" in the article/lead that allows a naive reader to appreciate the non-conscious nature of nociception. SmithBlue (talk) 05:48, 5 April 2008 (UTC)
[edit] History of terms
Anyone have info on the origins of "physiological pain"? SmithBlue (talk) 14:48, 5 April 2008 (UTC)
[edit] Assessment
I'm assessing this now, partly on the basis of what I expect it to be when we're done. If you disagree, then we can reassess it next month. WhatamIdoing (talk) 17:31, 5 April 2008 (UTC)
[edit] chronic pain sections
Heres a grab of chronic pains sections - has some references that will be relevent
[edit] Functional anatomy
The anatomy of the nociceptive system can be grossly divided into the peripheral and central nervous system. The peripheral nervous system consists of small myelinated and unmyelinated nerve fibers. These nerve fibers converge into a region of the spinal cord referred to as the dorsal horn. The dorsal horn is the first relay station in pain signal transmission. The next element of pain transmission includes nerve fibers that then travel to the thalamus. From the thalamus the next order of neurons ascend to the limbic system and sensory cortex. This accounts for the affective elements and discriminative of pain respectively.[1][2]
[edit] Nociception
Nociceptors convey information regarding damage or trauma from the body to the central nervous system, a process called nociception, where it is interpreted by the brain as pain. Nociception occurs in any tissue or organ in which pain signals arise secondary to a disease process or trauma. The nociception can also occur if there is dysfunction or damage to nerves themselves.[3]
[edit] Pathophysiology
Under persistent activation nociceptive transmission to the dorsal horn may induce a wind up phenomenon. This induces pathological changes that lower the threshold for pain signals to be transmitted. In addition it may generate nonnociceptive nerve fibers to respond to pain signals. Nonnociceptive nerve fibers may also be able to generate and transmit pain signals. In chronic pain this process is difficult to reverse or eradicate once established.[4]
