Nitrite reductase (cytochrome; ammonia-forming)

From Wikipedia, the free encyclopedia

In enzymology, a nitrite reductase (cytochrome; ammonia-forming) (EC 1.7.2.2) is an enzyme that catalyzes the chemical reaction

NH₃ + 2 H₂O + 6 ferricytochrome c nitrite + 6 ferrocytochrome c + 7 H⁺

The 3 substrates of this enzyme are NH₃, H₂O, and ferricytochrome c, whereas its 3 products are nitrite, ferrocytochrome c, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with a cytochrome as acceptor. The systematic name of this enzyme class is ammonia:ferricytochrome-c oxidoreductase. Other names in common use include cytochrome c nitrite reductase, and multiheme nitrite reductase. This enzyme participates in nitrogen metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1OAH, 2E80, and 2E81.

[edit] References

• IUBMB entry for 1.7.2.2
• BRENDA references for 1.7.2.2 (Recommended.)
• PubMed references for 1.7.2.2
• PubMed Central references for 1.7.2.2
• Google Scholar references for 1.7.2.2
• R, Kroneck PM (1999). "Structure of cytochrome c nitrite reductase". Nature. 400: 476–80. doi:10.1038/22802. PMID 10440380. 

[edit] External links

• IUBMB entry for 1.7.2.2

• KEGG entry for 1.7.2.2

• BRENDA entry for 1.7.2.2

• NiceZyme view of 1.7.2.2

• EC2PDB: PDB structures for 1.7.2.2

• PRIAM entry for 1.7.2.2

• PUMA2 entry for 1.7.2.2

• IntEnz: Integrated Enzyme entry for 1.7.2.2

• MetaCyc entry for 1.7.2.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0042279: nitrite reductase (cytochrome, ammonia-forming)

• AMIGO entry for GO code 0042279: nitrite reductase (cytochrome, ammonia-forming)