NADPH peroxidase

From Wikipedia, the free encyclopedia

In enzymology, a NADPH peroxidase (EC 1.11.1.2) is an enzyme that catalyzes the chemical reaction

NADPH + H⁺ + H₂O₂ NADP⁺ + 2 H₂O

The 3 substrates of this enzyme are NADPH, H⁺, and H₂O₂, whereas its two products are NADP⁺ and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptor (peroxidases). The systematic name of this enzyme class is NADPH:hydrogen-peroxide oxidoreductase. Other names in common use include TPNH peroxidase, NADP peroxidase, nicotinamide adenine dinucleotide phosphate peroxidase, TPN peroxidase, triphosphopyridine nucleotide peroxidase, and NADPH2 peroxidase.

[edit] References

• IUBMB entry for 1.11.1.2
• BRENDA references for 1.11.1.2 (Recommended.)
• PubMed references for 1.11.1.2
• PubMed Central references for 1.11.1.2
• Google Scholar references for 1.11.1.2
• CONN EE, KRAEMER LM, LIU PN, VENNESLAND B (1952). "The aerobic oxidation of reduced triphosphopyridine nucleotide by a wheat germ enzyme system". J. Biol. Chem. 194: 143–51. PMID 14927602. 

[edit] External links

The CAS registry number for this enzyme class is 9029-51-0.

• IUBMB entry for 1.11.1.2

• KEGG entry for 1.11.1.2

• BRENDA entry for 1.11.1.2

• NiceZyme view of 1.11.1.2

• EC2PDB: PDB structures for 1.11.1.2

• PRIAM entry for 1.11.1.2

• PUMA2 entry for 1.11.1.2

• IntEnz: Integrated Enzyme entry for 1.11.1.2

• MetaCyc entry for 1.11.1.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050137: NADPH peroxidase

• AMIGO entry for GO code 0050137: NADPH peroxidase