N-acetylhexosamine 1-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a N-acetylhexosamine 1-dehydrogenase (EC 1.1.1.240) is an enzyme that catalyzes the chemical reaction

N-acetyl-D-glucosamine + NAD⁺ N-acetyl-D-glucosaminate + NADH + H⁺

Thus, the two substrates of this enzyme are N-acetyl-D-glucosamine and NAD⁺, whereas its 3 products are N-acetyl-D-glucosaminate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase. Other names in common use include N-acetylhexosamine dehydrogenase, and N-acetyl-D-hexosamine dehydrogenase.

[edit] References

• IUBMB entry for 1.1.1.240
• BRENDA references for 1.1.1.240 (Recommended.)
• PubMed references for 1.1.1.240
• PubMed Central references for 1.1.1.240
• Google Scholar references for 1.1.1.240
• Horiuchi T and Kurokawa T (1989). "Purification and characterization of N-acetyl-D-hexosamine dehydrogenase from Pseudomonas sp no 53". Agric. Biol. Chem. 53: 1919–1925. 

[edit] External links

The CAS registry number for this enzyme class is 122785-18-6.

• IUBMB entry for 1.1.1.240

• KEGG entry for 1.1.1.240

• BRENDA entry for 1.1.1.240

• NiceZyme view of 1.1.1.240

• EC2PDB: PDB structures for 1.1.1.240

• PRIAM entry for 1.1.1.240

• PUMA2 entry for 1.1.1.240

• IntEnz: Integrated Enzyme entry for 1.1.1.240

• MetaCyc entry for 1.1.1.240

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050120: N-acetylhexosamine 1-dehydrogenase

• AMIGO entry for GO code 0050120: N-acetylhexosamine 1-dehydrogenase