Methanol dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a methanol dehydrogenase (EC 1.1.1.244) is an enzyme that catalyzes the chemical reaction

methanol + NAD⁺ formaldehyde + NADH + H⁺

Thus, the two substrates of this enzyme are methanol and NAD⁺, whereas its 3 products are formaldehyde, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is methanol:NAD+ oxidoreductase. This enzyme participates in methane metabolism.

[edit] References

• IUBMB entry for 1.1.1.244
• BRENDA references for 1.1.1.244 (Recommended.)
• PubMed references for 1.1.1.244
• PubMed Central references for 1.1.1.244
• Google Scholar references for 1.1.1.244
• Harder W, Attwood MM, Dijkhuizen L (1989). "Methanol metabolism in thermotolerant methylotrophic Bacillus strains involving a novel catabolic NAD-dependent methanol dehydrogenase as a key enzyme". Arch. Microbiol. 152: 280–8. doi:10.1007/BF00409664. PMID 2673121. 

[edit] External links

The CAS registry number for this enzyme class is 74506-37-9.

• IUBMB entry for 1.1.1.244

• KEGG entry for 1.1.1.244

• BRENDA entry for 1.1.1.244

• NiceZyme view of 1.1.1.244

• EC2PDB: PDB structures for 1.1.1.244

• PRIAM entry for 1.1.1.244

• PUMA2 entry for 1.1.1.244

• IntEnz: Integrated Enzyme entry for 1.1.1.244

• MetaCyc entry for 1.1.1.244

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050093: methanol dehydrogenase

• AMIGO entry for GO code 0050093: methanol dehydrogenase