Marchiafava-Bignami disease

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Marchiafava-Bignami disease
Classification and external resources
ICD-10 G37.1
ICD-9 341.8
DiseasesDB 31494
eMedicine neuro/204 
MeSH D054319

Marchiafava-Bignami disease is a progressive neurological disease characterized by corpus callosum demyelination and necrosis and subsequent atrophy.

Contents

[edit] Eponym

It was first described in 1903 by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker.[1][2]

[edit] Causes

It is classically associated with chronic alcoholics.

[edit] References

  1. ^ synd/2922 at Who Named It
  2. ^ E. Marchiafava, A. Bignami. Sopra un' alterazione del corpo calloso osservata da sogetti alcoolisti. Rivista di patologia nervosa e mentale, 1903, 8 (12): 544-549.

[edit] External links

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Pathology of the nervous system, primarily CNS (G00-G47, 320-349)
Inflammatory diseases
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Systemic atrophies
primarily affecting the CNS
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