Malonate CoA-transferase

From Wikipedia, the free encyclopedia

In enzymology, a malonate CoA-transferase (EC 2.8.3.3) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + malonate acetate + malonyl-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and malonate, whereas its two products are acetate and malonyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:malonate CoA-transferase. This enzyme is also called malonate coenzyme A-transferase. This enzyme participates in beta-alanine metabolism and propanoate metabolism.

[edit] References

• IUBMB entry for 2.8.3.3
• BRENDA references for 2.8.3.3 (Recommended.)
• PubMed references for 2.8.3.3
• PubMed Central references for 2.8.3.3
• Google Scholar references for 2.8.3.3
• HAYAISHI O (1955). "Enzymatic decarboxylation of malonic acid". J. Biol. Chem. 215: 125–36. PMID 14392148. 
• Takamura Y and Kitayama Y (1981). "Purification and some properties of malonate decarboxylase from Pseudomonas ovalis: an oligomeric enzyme with bifunctional properties". Biochem. Int. 3: 483–491. 

[edit] External links

The CAS registry number for this enzyme class is 9026-18-0.

• IUBMB entry for 2.8.3.3

• KEGG entry for 2.8.3.3

• BRENDA entry for 2.8.3.3

• NiceZyme view of 2.8.3.3

• EC2PDB: PDB structures for 2.8.3.3

• PRIAM entry for 2.8.3.3

• PUMA2 entry for 2.8.3.3

• IntEnz: Integrated Enzyme entry for 2.8.3.3

• MetaCyc entry for 2.8.3.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050078: malonate CoA-transferase

• AMIGO entry for GO code 0050078: malonate CoA-transferase