Long-chain-alcohol dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a long-chain-alcohol dehydrogenase (EC 1.1.1.192) is an enzyme that catalyzes the chemical reaction

a long-chain alcohol + 2 NAD⁺ + H₂O a long-chain carboxylate + 2 NADH + 2 H⁺

The 3 substrates of this enzyme are long-chain alcohol, NAD⁺, and H₂O, whereas its 3 products are long-chain carboxylate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is long-chain-alcohol:NAD+ oxidoreductase. Other names in common use include long-chain alcohol dehydrogenase, and fatty alcohol oxidoreductase. This enzyme participates in fatty acid metabolism.

[edit] References

• IUBMB entry for 1.1.1.192
• BRENDA references for 1.1.1.192 (Recommended.)
• PubMed references for 1.1.1.192
• PubMed Central references for 1.1.1.192
• Google Scholar references for 1.1.1.192
• Lee T (1979). "Characterization of fatty alcohol:NAD+ oxidoreductase from rat liver". J. Biol. Chem. 254: 2892–6. PMID 34610. 

[edit] External links

The CAS registry number for this enzyme class is 76774-36-2.

• IUBMB entry for 1.1.1.192

• KEGG entry for 1.1.1.192

• BRENDA entry for 1.1.1.192

• NiceZyme view of 1.1.1.192

• EC2PDB: PDB structures for 1.1.1.192

• PRIAM entry for 1.1.1.192

• PUMA2 entry for 1.1.1.192

• IntEnz: Integrated Enzyme entry for 1.1.1.192

• MetaCyc entry for 1.1.1.192

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050060: long-chain-alcohol dehydrogenase

• AMIGO entry for GO code 0050060: long-chain-alcohol dehydrogenase