Loi Estrada
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| The Honourable Luisa Ejercito Estrada |
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| In office June 30, 1998 – January 20, 2001 |
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| Preceded by | Amelita Ramos |
| Succeeded by | Jose Miguel Arroyo |
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| In office June 30, 2001 – June 30, 2007 |
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| Born | June 2, 1930 Iba, Zambales, Philippines |
| Political party | Pwersa ng Masang Pilipino |
| Spouse | Joseph Estrada |
| Religion | Roman Catholic |
Luisa Fernandez Pimentel-Ejercito (born June 2, 1930 in Iba, Zambales), better known as Luisa "Loi" Ejercito Estrada was a Filipino politician. She is the wife of former Philippine President Joseph Estrada, and was the thirteenth First Lady of the Philippines from 1998 to 2001. She was born to Rufino Pimentel and Manuela Fernandez. In 2001, she ran as a candidate of the opposition for a seat in the Senate. She won, and served in the 12th and the 13th Congress of the Philippines, making her the first First Lady to win a seat in the Senate. Her son, Jinggoy Ejercito Estrada is a senator. She is a psychiatrist by profession, known as very close to the poor. She was dubbed as "First Lady ng Masa" (First Lady of the Masses) because of her medical and outreach missions during her term.
She earned her medicine degree at the University of Santo Tomas (UST), after which she worked as a Professor in the UST Faculty of Medicine and Surgery, and a Physician at the UST Hospital and the National Center for Mental Health.
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| Preceded by Amelita Ramos |
First Lady of the Philippines 1998–2001 |
Succeeded by Jose Miguel Arroyo |


