Talk:Locus (genetics)

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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) Rated "high" as high school/SAT biology content. This goes together with allele. - tameeria 00:01, 19 February 2007 (UTC)

[edit] So

So, what does p16INK4a (or even p16^INK4a) mean? 82.18.21.208 10:10, 30 September 2006 (UTC)

What do you mean? That's not in the article. Maybe you should ask that question in the Reference Desk. Speaking of confusing stuff, what's with the fraction and symbols in the beginning? Is that part of the article? --JDitto 05:27, 27 November 2006 (UTC)

It looks like it was accidentally inserted during this edit. I have removed them. --Arcadian 05:35, 27 November 2006 (UTC)

Accidentally? Oh well. Thank you for your assistance. Have a nice day. --JDitto 05:43, 27 November 2006 (UTC)

In the last sentence of the first paragraph where it says that genome mapping is about saying what function is associated with a locus is reaching. Genome mapping is knowing what alleles are where. The purpose of these alleles is still largly unknown even as the Genome map is finished. So maybe it is true that, now, genome mapping wants to replace alleles with their biological function, but as the definition of mapping, this is reaching. Dave44000 21:47, 19 December 2006 (UTC)

[edit] Is 1 locus specific to a single gene?

I was wondering if someone could say whether there might be more than 1 gene at a locus. e.g. the locus used in the article, 6p21.3 I happen to know is CYP21 (21 hydroxylase), from the article I know that the locus is accurate to the sub-band, but how many genes are in a sub-band? Loci can be written to varying degrees of precision and I was thinking perhaps there should be something about precision in loci written from "chromosome 6" down to 6p21.3 and possibly beyond into sub-sub-bands. (I've never even seen seen "sub-sub-bands" before reading this article) --KX36 (talk) 14:00, 9 January 2008 (UTC)

I think you have a good question there. I would say that there can only be one gene in a locus since it is defined something like the specific position of a gene or other chromosomal marker. However, if you start talking about the number of genes in 6p21.3 there can most certainly be more than one (there is more than 50). I'm probably insulting somebody working with karyotypes here, but nowadays (post-human gene project) gene locations are mostly talked about in terms of bp-count from one gene. CYP21 (CYP21A2 - to be specific) would be said to be present at chr6:32114061-32117398. --LasseFolkersen (talk) 13:16, 18 March 2008 (UTC)