Lactaldehyde reductase (NADPH)

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In enzymology, a lactaldehyde reductase (NADPH) (EC 1.1.1.55) is an enzyme that catalyzes the chemical reaction

propane-1,2-diol + NADP⁺ L-lactaldehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are 1,2-propanediol and NADP⁺, whereas its 3 products are L-lactaldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propane-1,2-diol:NADP+ oxidoreductase. Other names in common use include lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate), reductase, NADP+-1,2-propanediol dehydrogenase, propanediol dehydrogenase, 1,2-propanediol:NADP+ oxidoreductase, and lactaldehyde reductase (NADPH).

[edit] References

• IUBMB entry for 1.1.1.55
• BRENDA references for 1.1.1.55 (Recommended.)
• PubMed references for 1.1.1.55
• PubMed Central references for 1.1.1.55
• Google Scholar references for 1.1.1.55
• GUPTA NK, ROBINSON WG (1960). "The enzymatic conversion of lactaldehyde to propanediol". J. Biol. Chem. 235: 1609–12. PMID 13830319. 

[edit] External links

The CAS registry number for this enzyme class is 9028-43-7.

• IUBMB entry for 1.1.1.55

• KEGG entry for 1.1.1.55

• BRENDA entry for 1.1.1.55

• NiceZyme view of 1.1.1.55

• EC2PDB: PDB structures for 1.1.1.55

• PRIAM entry for 1.1.1.55

• PUMA2 entry for 1.1.1.55

• IntEnz: Integrated Enzyme entry for 1.1.1.55

• MetaCyc entry for 1.1.1.55

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050039: lactaldehyde reductase (NADPH)

• AMIGO entry for GO code 0050039: lactaldehyde reductase (NADPH)