User:JonSDSUGrad/Sandbox/TEST1 CHRM5

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Cholinergic receptor, muscarinic 5
Identifiers
Symbol(s)	CHRM5; HM5; MGC41838
External IDs	OMIM: 118496 MGI: 109248 HomoloGene: 22697
Gene ontology Molecular Function: • rhodopsin-like receptor activity • phosphoinositide phospholipase C activity • receptor activity • muscarinic acetylcholine receptor activity Cellular Component: • plasma membrane • integral to plasma membrane • postsynaptic membrane Biological Process: • signal transduction • muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway • acetylcholine receptor signaling, muscarinic pathway • cell proliferation
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	1133	213788
Ensembl	ENSG00000184984	ENSMUSG00000074939
Uniprot	P08912	Q0VBI9
Refseq	NM_012125 (mRNA) NP_036257 (protein)	NM_205783 (mRNA) NP_991352 (protein)
Location	Chr 15: 32.14 - 32.14 Mb	Chr 2: 112.28 - 112.28 Mb
Pubmed search	[1]	[2]

Cholinergic receptor, muscarinic 5, also known as CHRM5, is a human gene.

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.^[1]

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