Talk:Interleukin 10

From Wikipedia, the free encyclopedia

	This article is within the scope of WikiProject Medicine. Please visit the project page for details or ask questions at the doctor's mess.
Start	This page has been rated as Start-Class on the quality assessment scale
Low	This article has been rated as Low-importance on the importance assessment scale

	MCB Portal This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
Stub	This article has been rated as Stub-Class on the assessment scale.
Mid	This article is on a subject of Mid-importance within molecular and cellular biology.
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need.

[edit] While

While I haven't researched IL-10 in any fashion since 1998, I believe that the cytokines that are inhibited by IL-10 on CD4+ T cells depended upon the species: IL-10 inhibits both Th1 and Th2 cytokines in human T cells (although there was debate as to whether there was a larger inhibition of Th1 cytokines), whereas it only significantly inhibited Th1 cytokines in mice.

Also, I believe that IL-10 could also facilitate antibody class switching in B cells, but that wasn't near my area of research. I don't have the references on me, but I can dig them up if someone wants more detail. Volantares 08:19, 23 August 2005 (UTC)

Please do. Your expertise is welcomed, and 7 yr old info is better than no info at all! JFW | T@lk 12:02, 23 August 2005 (UTC)

Wow guys, this info's nine year's old now. But rest assured, at a brief glance, the information's correct. However, with regard to what Volantares said above, IL-10 not just inhibits Th1 cytokine secretion, it inhibits the cells all together, contributing to Th2 prevailance. Diuness —Preceding signed but undated comment was added at 03:46, 5 October 2007 (UTC)